Gene therapy for glaucoma: treating a multifaceted, chronic disease.

  title={Gene therapy for glaucoma: treating a multifaceted, chronic disease.},
  author={Terete Borr{\'a}s and Curtis R. Brandt and Robert W Nickells and Robert Ritch},
  journal={Investigative ophthalmology & visual science},
  volume={43 8},
Glaucoma is a progressive optic neuropathy. It is characterized by a particular pattern of optic nerve head and visual field damage resulting from a number of different diseases that affect the eye. Many of these are associated with elevated intraocular pressure (IOP), which is the most common known associated risk factor, but not the only risk factor, for the development and/or progression of glaucomatous damage. The final common pathologic event is retinal ganglion cell (RGC) death. As such… CONTINUE READING


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TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2002
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