Gene therapy for carcinoma of the breast: Therapeutic genetic correction strategies

  title={Gene therapy for carcinoma of the breast: Therapeutic genetic		  correction strategies},
  author={Patrice S. Obermiller and David L. Tait and Jeffrey T. Holt},
  journal={Breast Cancer Research},
  pages={28 - 31}
Gene therapy is a therapeutic approach that is designed to correct specific molecular defects that contribute to the cause or progression of cancer. Genes that are mutated or deleted in cancers include the cancer susceptibility genes p53 and BRCA1. Because mutational inactivation of gene function is specific to tumor cells in these settings, cancer gene correction strategies may provide an opportunity for selective targeting without significant toxicity for normal nontumor cells. Both p53 and… CONTINUE READING

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