Gene therapy for amyotrophic lateral sclerosis and other motor neuron diseases.

@article{Alisky2000GeneTF,
  title={Gene therapy for amyotrophic lateral sclerosis and other motor neuron diseases.},
  author={Joseph Martin Alisky and Beverly L. Davidson},
  journal={Human gene therapy},
  year={2000},
  volume={11 17},
  pages={2315-29}
}
There are several incurable diseases of motor neuron degeneration, including amyotrophic lateral sclerosis (ALS), primary lateral sclerosis, hereditary spastic hemiplegia, spinal muscular atrophy, and bulbospinal atrophy. Advances in gene transfer techniques coupled with new insights into molecular pathology have opened promising avenues for gene therapy aimed at halting disease progression. Nonviral preparations and recombinant adenoviruses, adeno-associated viruses, herpesviruses, and… CONTINUE READING
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