Gene therapy approaches to prevent corneal graft rejection: where do we stand?

@article{Ritter2013GeneTA,
  title={Gene therapy approaches to prevent corneal graft rejection: where do we stand?},
  author={Thomas Ritter and Mieszko M Wilk and Mikhail S. Nosov},
  journal={Ophthalmic research},
  year={2013},
  volume={50 3},
  pages={
          135-40
        }
}
Cornea transplantation (penetrating keratoplasty) is the most frequently performed transplant procedure in humans. Despite advances in microsurgery and immunosuppressive treatment protocols, a significant number of corneal grafts still undergo immune-mediated allograft rejection. Topical treatment with corticosteroids is currently the gold standard and while this treatment is effective in many corneal transplant patients, it is much less effective in 'high-risk' patients with previous episodes… CONTINUE READING

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