Gene therapeutics: the future of brain tumor therapy?

  title={Gene therapeutics: the future of brain tumor therapy?},
  author={Jennifer L. Cutter and Kazuhiko Kurozumi and E. A. Chiocca and B. Devinder Kaur},
  journal={Expert review of anticancer therapy},
  volume={6 7},
Primary glioblastoma multiforme is an aggressive brain tumor that has no cure. Current treatments include gross resection of the tumor, radiation and chemotherapy. Despite valiant efforts, prognosis remains dismal. A promising new technique involves the use of oncolytic viruses that can specifically replicate and lyse in cancers, without spreading to normal tissues. Currently, these are being tested in relevant preclinical models and clinical trials as a therapeutic modality for many types of… CONTINUE READING