Gene survey of the pathogenic protozoan Trypanosoma cruzi.

  title={Gene survey of the pathogenic protozoan Trypanosoma cruzi.},
  author={Betina M. Porcel and Anh Nhi Tran and Martti Tammi and Zolt{\'a}n Ny{\'a}r{\'a}dy and Maria Ryd{\aa}ker and Tur{\'a}n P{\'e}ter Urm{\'e}nyi and Edson Rondinelli and U. Pettersson and Bj{\"o}rn Andersson and Lena {\AA}slund},
  journal={Genome research},
  volume={10 8},
We have performed a survey of the active genes in the important human pathogen Trypanosoma cruzi by analyzing 5013 expressed sequence tags (ESTs) generated from a normalized epimastigote cDNA library. Clustering of all sequences resulted in 771 clusters, comprising 54% of the ESTs. In total, the ESTs corresponded to 3054 transcripts that might represent one-fourth of the total gene repertoire in T. cruzi. About 33% of the T. cruzi transcripts showed similarity to sequences in the public… CONTINUE READING