Gene structure of the murine N-methyl D-aspartate receptor subunit NR2C.

@article{Suchanek1995GeneSO,
  title={Gene structure of the murine N-methyl D-aspartate receptor subunit NR2C.},
  author={Bettina Suchanek and P. H. Seeburg and Rolf Sprengel},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 1},
  pages={41-4}
}
The murine N-methyl D-aspartate receptor subunit NR2C (epsilon-3) is encoded by a unique gene composed of 12 translated and three 5'-untranslated exons that spread over approximately 20 kilobases of genomic sequence. The GC-rich promoter that lacks TATA- and CAAT-positioning elements has two transcriptional start sites separated by 18 base pairs. One of these sites is located in a conserved initiator motif and, together with the first four exons, specifies the 5'-untranslated sequence of 772… CONTINUE READING