Gene silencing reveals a crucial role for anti-lipopolysaccharide factors from Penaeus monodon in the protection against microbial infections.

@article{Ponprateep2012GeneSR,
  title={Gene silencing reveals a crucial role for anti-lipopolysaccharide factors from Penaeus monodon in the protection against microbial infections.},
  author={Sirikwan Ponprateep and Sirinit Tharntada and Kunlaya Somboonwiwat and Anchalee Tassanakajon},
  journal={Fish & shellfish immunology},
  year={2012},
  volume={32 1},
  pages={26-34}
}
Anti-lipopolysaccharide factors (ALFs) are antimicrobial peptides previously identified in various crustaceans. Out of five isoforms identified in Penaeus monodon, ALFPm3 is the best characterized, exhibits antibacterial and antifungal activities and can protect the shrimp from viral infections. Herein, the most recent identified ALFPm, called ALFPm6, is characterized for its potential role in the shrimp's immunity. RNA interference-mediated gene silencing was used to study the function of… CONTINUE READING

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Antimicrobial peptides in marine invertebrate health and disease.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences • 2016

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