Gene signatures of testicular seminoma with emphasis on expression of ets variant gene 4

  title={Gene signatures of testicular seminoma with emphasis on expression of ets variant gene 4},
  author={Isabella Gashaw and Ruth Gr{\"u}mmer and Ludger Klein-Hitpass and Oliver Dushaj and Martin W Bergmann and Ralph Brehm and Rainer Grobholz and Sabine Kliesch and Tanja Pascale Neuvians and Kurt Werner Schmid and C. von. Ostau and E. Winterhager},
  journal={Cellular and Molecular Life Sciences CMLS},
Gene expression patterns of testicular seminoma were analysed applying oligonucleotide microarrays in 40 specimens of different tumour stages (pT1, pT2, pT3) and in normal testes. Transcripts of maternally expressed 3 transcripts were expressed in seminoma without correlation with delta-like 1 homologue expression indicating an impaired imprinting status in seminoma. Interestingly, the transcripts of bromodomain-containing 2 and nuclear autoantigenic sperm protein associated with… CONTINUE READING


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