Gene set enrichment analysis provides insight into novel signalling pathways in breast cancer stem cells

Abstract

Background:Tumour-initiating cells (TICs) or cancer stem cells can exist as a small population in malignant tissues. The signalling pathways activated in TICs that contribute to tumourigenesis are not fully understood.Methods:Several breast cancer cell lines were sorted with CD24 and CD44, known markers for enrichment of breast cancer TICs. Tumourigenesis… (More)
DOI: 10.1038/sj.bjc.6605468

Topics

5 Figures and Tables

Slides referencing similar topics