Gene set enrichment analysis highlights different gene expression profiles in whole blood samples X-irradiated with low and high doses.

@article{ElSaghire2013GeneSE,
  title={Gene set enrichment analysis highlights different gene expression profiles in whole blood samples X-irradiated with low and high doses.},
  author={Houssein El-Saghire and Hubert Thierens and Pieter Monsieurs and Arlette Michaux and Charlot Vandevoorde and Sarah Baatout},
  journal={International journal of radiation biology},
  year={2013},
  volume={89 8},
  pages={628-38}
}
PURPOSE Health risks from exposure to low doses of ionizing radiation (IR) are becoming a concern due to the rapidly growing medical applications of X-rays. Using microarray techniques, this study aims for a better understanding of whole blood response to low and high doses of IR. MATERIALS AND METHODS Aliquots of peripheral blood samples were irradiated with 0, 0.05, and 1 Gy X-rays. RNA was isolated and prepared for microarray gene expression experiments. Bioinformatic approaches, i.e… CONTINUE READING
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