Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast

@article{Nurse1981GeneRI,
  title={Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast},
  author={P. Nurse and Yvonne Bissett},
  journal={Nature},
  year={1981},
  volume={292},
  pages={558-560}
}
The control regulating commitment to the cell division cycle of eukaryotes seems to occur before the initiation of DNA replication1–4. In the budding yeast Saccharomyces cerevisiae, this control is called start and is the earliest gene-controlled event of the cell cycle3–5. A haploid cell which has completed start is committed to cell division and unable to undergo alternative developmental fates such as conjugation. Here, we describe an analogous start control in the fission yeast… CONTINUE READING

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