Gene regulatory networks: a new conceptual framework to analyse breast cancer behaviour.

@article{Demicheli2011GeneRN,
  title={Gene regulatory networks: a new conceptual framework to analyse breast cancer behaviour.},
  author={Romano Demicheli and Danila Coradini},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2011},
  volume={22 6},
  pages={1259-65}
}
The study of complex systems has clearly evidenced that a few overall behavioural properties cannot be inferred from the properties of their single parts and are rather determined by their architecture. Such an approach has been recently proposed in biology to understand genome functioning and in oncology to endeavour a more consistent explanation of the variegated cancer behaviours. In the present perspective, we summarise the basic concepts of the proposed global approach and then we… CONTINUE READING