Gene regulation of mammalian long non-coding RNA

@article{Bunch2017GeneRO,
  title={Gene regulation of mammalian long non-coding RNA},
  author={Heeyoun Bunch},
  journal={Molecular Genetics and Genomics},
  year={2017},
  volume={293},
  pages={1-15}
}
  • Heeyoun Bunch
  • Published 2017
  • Biology, Medicine
  • Molecular Genetics and Genomics
RNA polymerase II (Pol II) transcribes two classes of RNAs, protein-coding and non-protein-coding (ncRNA) genes. ncRNAs are also synthesized by RNA polymerases I and III (Pol I and III). In humans, the number of ncRNA genes exceeds more than twice that of protein-coding genes. However, the history of studying Pol II-synthesized ncRNA is relatively short. Since early 2000s, important biological and pathological functions of these ncRNA genes have begun to be discovered and intensively studied… Expand
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