Gene regulation by engineered CRISPR-Cas systems.

  title={Gene regulation by engineered CRISPR-Cas systems.},
  author={Peter C. Fineran and Ron L. Dy},
  journal={Current opinion in microbiology},
The clustered regularly interspaced short palindromic repeat (CRISPR) arrays and their CRISPR associated (Cas) proteins constitute adaptive immune systems in bacteria and archaea that provide protection from bacteriophages, plasmids and other mobile genetic elements (MGEs). Recently, the ability to direct these systems to DNA in a sequence-specific manner… CONTINUE READING
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