Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats.

@article{Chen2008GeneRB,
  title={Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats.},
  author={Ling-Ling Chen and Gordon G. Carmichael},
  journal={Cell cycle},
  year={2008},
  volume={7 21},
  pages={3294-301}
}
The Alu elements are conserved approximately 300 nucleotide long repeat sequences that belong to the SINE family of retrotransposons found abundantly in primate genomes. Although the vast majority of Alu elements appear to be genetically inert, it has been tempting to consider the great majority of them as "junk DNA." However, a growing line of evidence suggests that transcribed Alu RNAs are in fact functionally involved in a number of diverse biological processes. Pairs of inverted Alu repeats… CONTINUE READING

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