Gene regulation and large-scale chromatin organization in the nucleus

@article{Dillon2006GeneRA,
  title={Gene regulation and large-scale chromatin organization in the nucleus},
  author={N. Dillon},
  journal={Chromosome Research},
  year={2006},
  volume={14},
  pages={117-126}
}
  • N. Dillon
  • Published 2006
  • Biology, Medicine
  • Chromosome Research
Regulation of gene expression involves a number of different levels of organization in the cell nucleus. The main agents of transcriptional control are the cis-acting sequences in the immediate vicinity of a gene, which combine to form the functional unit or domain. Contacts between these sequences through the formation of chromatin loops forms the most basic level of organization. The activity of functional domains is also influenced by higher order chromatin structures that impede or permit… Expand
88 Citations

Figures and Topics from this paper

CP27: Expression, Regulation, and Function of a Chromatin Complex Member
Transcription factories: genome organization and gene regulation.
  • 175
  • PDF
Global Chromatin Domain Organization of the Drosophila Genome
  • 79
  • PDF
Estrogen represses gene expression through reconfiguring chromatin structures
  • 18
  • PDF
Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules
  • 272
  • PDF
A systems biology approach to understanding cis-regulatory module function.
  • 43
Boundaries in vertebrate genomes: different solutions to adequately insulate gene expression domains.
  • 24
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 83 REFERENCES
Long-range chromatin regulatory interactions in vivo
  • 599
  • PDF
The effect of distance on long-range chromatin interactions.
  • 185
  • PDF
Looping and interaction between hypersensitive sites in the active beta-globin locus.
  • 1,306
  • PDF
The role of enhancers as centres for general transcription factor recruitment.
  • 130
Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription.
  • 649
  • PDF
Active genes dynamically colocalize to shared sites of ongoing transcription
  • 1,034
  • PDF
Spatial organization of active and inactive genes and noncoding DNA within chromosome territories
  • 242
  • PDF
...
1
2
3
4
5
...