Gene regulation: Repositioning tunes expression


increasingly three-dimensional — studies in the past few years suggest that repositioning of loci within the nucleus is important for coordinated expression. A recent paper reveals that an active, multistep mechanism regulates interactions between loci and directs them to nuclear subcompartments, thereby specifying levels of transcription. Nunez, Kwon and… (More)
DOI: 10.1038/nrg2377