Gene profiling of human fetal and adult adrenals.

@article{Rainey2001GenePO,
  title={Gene profiling of human fetal and adult adrenals.},
  author={William E. Rainey and Bruce Richard Carr and Zi Ning Wang and C. Richard Parker},
  journal={The Journal of endocrinology},
  year={2001},
  volume={171 2},
  pages={209-15}
}
The mechanisms that lead to the steroidogenic differences in the human fetal adrenal (HFA) and adult adrenal gland are not known. However, gene expression clearly plays a critical role in defining their distinct steroidogenic and structural phenotypes. We used DNA microarrays to compare expression levels of several thousand transcripts between the HFA and adult adrenal gland. Total RNA was isolated from 18 HFA and 12 adult adrenal glands. Samples of total RNA were used to make five pools of… CONTINUE READING

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