Gene profiling analysis of ALVAC infected human monocyte derived dendritic cells.

@article{Harenberg2008GenePA,
  title={Gene profiling analysis of ALVAC infected human monocyte derived dendritic cells.},
  author={Anke Harenberg and Florine Guillaume and Elizabeth J. Ryan and Nicolas Burdin and Franca Spada},
  journal={Vaccine},
  year={2008},
  volume={26 39},
  pages={5004-13}
}
The recombinant canarypox virus ALVAC is being extensively studied as vaccine vector for the development of new vaccine strategies against chronic infectious diseases and cancer. However, the mechanisms by which ALVAC initiates the immune response have not been completely elucidated. In order to determine the type of innate immunity triggered by ALVAC, we characterized the gene expression profile of human monocyte derived dendritic cells (MDDCs) upon ALVAC infection. These cells are permissive… CONTINUE READING

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