Gene polymorphisms of ACE and the angiotensin receptor AT2R1 influence serum ACE levels in sarcoidosis.

@article{Biller2009GenePO,
  title={Gene polymorphisms of ACE and the angiotensin receptor AT2R1 influence serum ACE levels in sarcoidosis.},
  author={Heike Biller and Bertram Ruprecht and Karoline Iris Gaede and Joachim M{\"u}ller-Quernheim and Gernot Zissel},
  journal={Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG},
  year={2009},
  volume={26 2},
  pages={139-46}
}
Angiotensin converting enzyme (ACE) is thought to influence susceptibility, disease progression, and/or outcome of sarcoidosis by functional mutations/polymorphisms of the ACE gene, such as the ACE gene deletion/insertion (D/I) polymorphism or the angiotensin receptors like the angiotensin II receptor type 1 (AT2R1) A1166 --> C polymorphism. The aim of our… CONTINUE READING