Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study.

@article{Lim2007GenenutrientIA,
  title={Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study.},
  author={Unhee Lim and Sophia Wang and Patricia A Hartge and Wendy Cozen and Linda E. Kelemen and Stephen J. Chanock and Scott M Davis and Aaron Blair and Maryjean Schenk and Nathaniel Rothman and Qing Lan},
  journal={Blood},
  year={2007},
  volume={109 7},
  pages={3050-9}
}
We previously reported a lower risk of non-Hodgkin lymphoma (NHL) associated with high consumption of vitamin B6 and methionine, dietary determinants of one-carbon metabolism. Evidence has linked genetic variants involved in one-carbon metabolism to NHL. We investigated 30 polymorphisms in 18 genes for their main effect on NHL among 1141 incident cases and 949 population-based controls and examined gene-nutrient interactions in a subgroup of 386 cases and 319 controls who provided detailed food… CONTINUE READING
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