Gene mutations of 23S rRNA associated with clarithromycin resistance in Helicobacter pylori strains isolated from Korean patients.

@article{Kim2008GeneMO,
  title={Gene mutations of 23S rRNA associated with clarithromycin resistance in Helicobacter pylori strains isolated from Korean patients.},
  author={Jung Mogg Kim and Joo Sung Kim and Nayoung Kim and Yeoung-Jeon Kim and In Young Kim and Young Joon Chee and C Lee and Hyun Chae Jung},
  journal={Journal of microbiology and biotechnology},
  year={2008},
  volume={18 9},
  pages={1584-9}
}
Although resistance of Helicobacter pylori to clarithromycin is a major cause of failure of eradication therapies, little information is available regarding gene mutations of clarithromycin-resistant primary and secondary H. pylori isolates in Korea. In the present study, we examined gene mutations of H. pylori 23S rRNA responsible for resistance to clarithromycin. DNA sequences of the 23S rRNA gene in 21 primary clarithromycin-resistant and 64 secondary clarithromycin-resistant strains were… CONTINUE READING

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Antibiotic resistance of Helicobacter pylori isolated from Korean patients

  • J. M. Kim
  • Korean J. Gastroenterol
  • 2006

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