Gene genealogies strongly distorted by weakly interfering mutations in constant environments.

@article{Seger2010GeneGS,
  title={Gene genealogies strongly distorted by weakly interfering mutations in constant environments.},
  author={Jon Seger and Wendy A Smith and Jarom J Perry and Jessalynn Hunn and Zofia A Kaliszewska and Luciano La Sala and Luciana M. Pozzi and Victoria J. Rowntree and Frederick R. Adler},
  journal={Genetics},
  year={2010},
  volume={184 2},
  pages={529-45}
}
Neutral nucleotide diversity does not scale with population size as expected, and this "paradox of variation" is especially severe for animal mitochondria. Adaptive selective sweeps are often proposed as a major cause, but a plausible alternative is selection against large numbers of weakly deleterious mutations subject to Hill-Robertson interference. The mitochondrial genealogies of several species of whale lice (Amphipoda: Cyamus) are consistently too short relative to neutral-theory… CONTINUE READING