Gene for lipoamide dehydrogenase maps to human chromosome 7.


The gene for lipoamide dehydrogenase (LD) has been assigned to human chromosome 7 based on filter hybridization analysis of genomic DNA from rodent-human somatic cell hybrids using a cDNA probe for human LD. No indication of multiple copies of the gene was found, in accordance with previous evidence that LD in the pyruvate, alpha-ketoglutarate, and branched chain alpha-ketoacid dehydrogenase complexes is genetically as well as biochemically identical.


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@article{Otulakowski1988GeneFL, title={Gene for lipoamide dehydrogenase maps to human chromosome 7.}, author={Gail Otulakowski and B. H. Robinson and Huntington F. Willard}, journal={Somatic cell and molecular genetics}, year={1988}, volume={14 4}, pages={411-4} }