Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D.

@article{Sparkes1983GeneFH,
  title={Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D.},
  author={Robert S. Sparkes and A. Linn Murphree and R W Lingua and Maryellen C. Sparkes and Leigh L. Field and Steve J. Funderburk and Williams F. Benedict},
  journal={Science},
  year={1983},
  volume={219 4587},
  pages={971-3}
}
Evaluation of three families with hereditary retinoblastoma demonstrates close linkage of the gene for this tumor with the genetic locus for esterase D. These results assign the gene for the hereditary form of retinoblastoma to band q14 on chromosome 13, the same region which is affected in the chromosome deletion form of this eye tumor, and therefore suggest a common underlying mechanism in the pathogenesis of these two forms of retinoblastoma. 

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