Gene expression signatures in breast cancer distinguish phenotype characteristics, histologic subtypes, and tumor invasiveness.

@article{Pedraza2010GeneES,
  title={Gene expression signatures in breast cancer distinguish phenotype characteristics, histologic subtypes, and tumor invasiveness.},
  author={Vincente Pedraza and Jos{\'e} Antonio G{\'o}mez-Capilla and Ge{\`o}rgia Escaram{\'i}s and Carolina B Gomez and Pablo Torn{\'e} and Jose M Rivera and Angel Martı́nez Gil and Patricia Araque and Nicol{\'a}s Olea and Xavier Estivill and Mar{\'i}a Esther F{\'a}rez-Vidal},
  journal={Cancer},
  year={2010},
  volume={116 2},
  pages={486-96}
}
BACKGROUND The development of reliable gene expression profiling technology is having an increasing impact on the understanding of breast cancer biology. METHODS In this study, microarray analysis was performed to establish gene signatures for different breast cancer phenotypes, to determine differentially expressed gene sequences at different stages of the disease, and to identify sequences with biologic significance for tumor progression. Samples were taken from patients before their… CONTINUE READING

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