Gene expression signature of lymphocyte in acute lymphoblastic leukemia patients immediately after total body irradiation.

Abstract

Molecular mechanisms involved in TBI preconditioning before allogenetic transplantation remain unclear. To elucidate possible signaling pathway in it, gene expression profiles of peripheral lymphocytes were compared between samples 24h after each 4.5 Gy total body irradiation treatment (total 9 Gy) from 4 adult ALL patients. 478 significant expressed genes… (More)
DOI: 10.1016/j.leukres.2010.12.026

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