Gene expression responses of threespine stickleback to salinity: implications for salt-sensitive hypertension

@inproceedings{Wang2014GeneER,
  title={Gene expression responses of threespine stickleback to salinity: implications for salt-sensitive hypertension},
  author={Gang Wang and Ence Yang and Kerri J. Smith and Yong Zeng and Guoli Ji and Richard Connon and Nann A Fangue and James J. Cai},
  booktitle={Front. Genet.},
  year={2014}
}
Despite recent success with genome-wide association studies (GWAS), identifying hypertension (HTN)-susceptibility loci in the general population remains difficult. Here, we present a novel strategy to address this challenge by studying salinity adaptation in the threespine stickleback, a fish species with diverse salt-handling ecotypes. We acclimated native freshwater (FW) and anadromous saltwater (SW) threespine sticklebacks to fresh, brackish, and sea water for 30 days, and applied RNA… CONTINUE READING
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Gene expression responses of threespine stickleback to salinity: implications for salt-sensitive hypertension

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This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums

  • Wang, Yang, +5 authors Cai
  • Frontiers in Genetics
  • 2014

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