Gene expression profiling reveals sequential changes in gastric tubular adenoma and carcinoma in situ.

@article{Lee2005GeneEP,
  title={Gene expression profiling reveals sequential changes in gastric tubular adenoma and carcinoma in situ.},
  author={Chang Hee Lee and Seung-Hyun Bang and Seung-Koo Lee and Kyu-Young Song and In-Chul Lee},
  journal={World journal of gastroenterology},
  year={2005},
  volume={11 13},
  pages={1937-45}
}
AIM To analyze the expression profiles of premalignant and/or preclinical lesions of gastric cancers. METHODS We analyzed the expression profiles of normal gastric pit, tubular adenoma and carcinoma in situ using microdissected cells from routine gastric biopsies. For the DNA microarray analysis of formalin-fixed samples, we developed a simple and reproducible RNA extraction and linear amplification procedure applying two polymerase-binding sites. The amplification procedure took only 8 h and… CONTINUE READING
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