Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia.

@article{Middleton2002GeneEP,
  title={Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia.},
  author={Frank A. Middleton and Karoly Mirnics and Joseph N. Pierri and David A. Lewis and Pat Levitt},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 7},
  pages={2718-29}
}
Dysfunction of the dorsal prefrontal cortex (PFC) in schizophrenia may be associated with alterations in the regulation of brain metabolism. To determine whether abnormal expression of genes encoding proteins involved in cellular metabolism contributes to this dysfunction, we used cDNA microarrays to perform gene expression profiling of all major metabolic… CONTINUE READING