Gene expression profiling predicts clinical outcome of breast cancer

@article{Veer2002GeneEP,
  title={Gene expression profiling predicts clinical outcome of breast cancer},
  author={L. J. Veer and H. Dai and M. Vijver and Y. He and A. Hart and M. Mao and H. Peterse and K. V. D. Kooy and M. Marton and A. Witteveen and G. Schreiber and R. Kerkhoven and C. Roberts and P. Linsley and R. Bernards and S. Friend},
  journal={Nature},
  year={2002},
  volume={415},
  pages={530-536}
}
Breast cancer patients with the same stage of disease can have markedly different treatment responses and overall outcome. [...] Key Method Here we used DNA microarray analysis on primary breast tumours of 117 young patients, and applied supervised classification to identify a gene expression signature strongly predictive of a short interval to distant metastases (‘poor prognosis’ signature) in patients without tumour cells in local lymph nodes at diagnosis (lymph node negative).Expand
Indications for Prognostic Gene Expression Profiling in Early Breast Cancer
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Clinical utility of gene-expression signatures in early stage breast cancer
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