Gene expression profiling of the retina after transcorneal electrical stimulation in wild-type Brown Norway rats.

@article{Willmann2011GeneEP,
  title={Gene expression profiling of the retina after transcorneal electrical stimulation in wild-type Brown Norway rats.},
  author={Gabriel Willmann and Karin Sch{\"a}ferhoff and Manuel Dominik Fischer and Blanca Arango-Gonzalez and Sylvia Bolz and Lubka Naycheva and Tobias R{\"o}ck and Michael Bonin and Karl Ulrich Bartz-Schmidt and Eberhart Zrenner and Andreas Schatz and Florian Gekeler},
  journal={Investigative ophthalmology \& visual science},
  year={2011},
  volume={52 10},
  pages={
          7529-37
        }
}
PURPOSE Transcorneal electrical stimulation (TES) has been beneficial in several neurodegenerative ocular diseases, but the exact mechanisms remain to be elucidated. This study was conducted to investigate the effects of TES on the retinas of wild-type Brown Norway (BN) rats by gene expression profiling and to assess its effects on retinal function and morphology. METHODS TES was applied to BN wild-type rat retinas in vivo for 1 hour (1-ms biphasic pulses at 20 Hz; 200 μA). RNA was isolated… 

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