Gene expression profiling of primary cutaneous melanoma and clinical outcome.

  title={Gene expression profiling of primary cutaneous melanoma and clinical outcome.},
  author={V{\'e}ronique J. L. Winnepenninckx and Vladimir Lazar and Stefan Michiels and Philippe Dessen and Marguerite Stas and Soledad R. Alonso and M Avril and Pablo Luis Ortiz Romero and Thomas Robert and Ovidiu Balacescu and A. M. M. Eggermont and Gilbert M. Lenoir and Alain Sarasin and Thomas Tursz and Joost J. van den Oord and Alain Spatz},
  journal={Journal of the National Cancer Institute},
  volume={98 7},
BACKGROUND Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective collections of frozen tumors. To identify differentially expressed genes that may be involved in melanoma progression and prognosis, we investigated the relationship between gene expression profiles and clinical outcome in a cohort of patients with primary melanoma. METHODS Labeled complementary RNA (cRNA) from each tissue sample was hybridized to a pangenomic 44K 60… CONTINUE READING
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