Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis.

@article{Bracko2012GeneEP,
  title={Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis.},
  author={Oliver Bracko and Tatjana Singer and Stefan Aigner and Marlen Knobloch and Beate Winner and Jasodhara Ray and Gregory D Clemenson and Hoonkyo Suh and Sebastien Couillard-Despres and Ludwig Aigner and Fred H. Gage and Sebastian Jessberger},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2012},
  volume={32 10},
  pages={
          3376-87
        }
}
Neural stem cells (NSCs) generate neurons throughout life in the hippocampal dentate gyrus (DG). How gene expression signatures differ among NSCs and immature neurons remains largely unknown. We isolated NSCs and their progeny in the adult DG using transgenic mice expressing a GFP reporter under the control of the Sox2 promoter (labeling NSCs) and transgenic mice expressing a DsRed reporter under the control of the doublecortin (DCX) promoter (labeling immature neurons). Transcriptome analyses… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 73 CITATIONS

The Nuclear Receptor REV-ERBα Regulates Fabp7 and Modulates Adult Hippocampal Neurogenesis

  • PloS one
  • 2014
VIEW 18 EXCERPTS
CITES RESULTS, BACKGROUND & METHODS
HIGHLY INFLUENCED

Insulin-like Growth Factor II: An Essential Adult Stem Cell Niche Constituent in Brain and Intestine

  • Stem cell reports
  • 2019
VIEW 7 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2014
VIEW 3 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

Galantamine promotes adult hippocampal neurogenesis via M₁ muscarinic and α7 nicotinic receptors in mice.

  • The international journal of neuropsychopharmacology
  • 2014
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2012
2019

CITATION STATISTICS

  • 14 Highly Influenced Citations

  • Averaged 8 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 64 REFERENCES

Similar Papers

Loading similar papers…