Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal.

@article{Wang2015GeneexpressionPO,
  title={Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal.},
  author={Teresa Yi Wen Wang and Roel C H Vermeulen and Wei Hu and Gang Liu and Xiaohui Xiao and Yuriy O. Alekseyev and Jun Xu and Boris Reiss and Katrina A Steiling and George Stanley Downward and Daniel N. Silverman and Fusheng Wei and Guanghong Wu and Jingyu Li and Marc E. Lenburg and Nathaniel Rothman and Avrum Spira and Qing Lan},
  journal={Carcinogenesis},
  year={2015},
  volume={36 12},
  pages={
          1494-501
        }
}
In China's rural counties of Xuanwei and Fuyuan, lung cancer rates are among the highest in the world. While the elevated disease risk in this population has been linked to the usage of smoky (bituminous) coal as compared to smokeless (anthracite) coal, the underlying molecular changes associated with this exposure remains unclear. To understand the physiologic effects of smoky coal exposure, we analyzed the genome-wide gene-expression profiles in buccal epithelial cells collected from healthy… CONTINUE READING
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