Gene expression profiling in the human middle cerebral artery after cerebral ischemia.

@article{Vikman2006GeneEP,
  title={Gene expression profiling in the human middle cerebral artery after cerebral ischemia.},
  author={Petter J Vikman and L. Edvinsson},
  journal={European journal of neurology},
  year={2006},
  volume={13 12},
  pages={1324-32}
}
We have investigated the gene expression in human middle cerebral artery (MCA) after ischemia. Ischemic stroke affects the perfusion in the affected area and experimental cerebral ischemia results in upregulation of vasopressor receptors in the MCA leading to the ischemic area. We obtained human MCA samples distributing to the ischemic area, 7-10 days post-stroke. The gene expression was examined with real-time polymerase chain reaction (PCR) and microarray, proteins were studied with… CONTINUE READING