Gene-expression profiling in pancreatic cancer.

  title={Gene-expression profiling in pancreatic cancer.},
  author={Pedro P Lopez-Casas and Luis Andr{\'e}s L{\'o}pez-Fern{\'a}ndez},
  journal={Expert review of molecular diagnostics},
  volume={10 5},
Pancreatic cancer has one of the worst prognoses, owing principally to a late diagnosis and the absence of good treatments. In the last 5 years, up to 12 molecular pathways involved in pancreatic cancer have been described. Global gene-expression profiling and the use of microarray databases have allowed the identification of hundreds of genes that are differentially expressed in pancreatic cancer. However, validation of these genes as biomarkers for early diagnosis, prognosis or treatment… CONTINUE READING

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