Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses

@inproceedings{Zheng2015GeneEP,
  title={Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses},
  author={Junying Zheng and Junru R Wang and Myl{\`e}ne Pouliot and Simon Authier and Daohong Zhou and David S. Loose and Martin Hauer-Jensen},
  booktitle={BMC Genomics},
  year={2015}
}
Although extensive studies have investigated radiation-induced injuries in particular gastrointestinal (GI) segments, a systematic comparison among the different segments on the basis of mode, magnitude and mechanism has not been reported. Here, a comparative study of segment-specific molecular and cellular responses was performed on jejunum, ileum and colon obtained at three time points (4, 7 and 12 days after irradiation) from non-human primate (Rhesus macaque) models exposed to 6.7 Gy or 7.4… CONTINUE READING
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