Gene expression profiling in autoimmune noninfectious uveitis disease.

  title={Gene expression profiling in autoimmune noninfectious uveitis disease.},
  author={Zhuqing Li and Baoying Liu and Arvydas Maminishkis and Sankaranarayana Pillai Mahesh and Steven Yeh and Julie C. Lew and Wee Kiak Lim and H. Nida Sen and Grace Clarke and Ronald Buggage and Sheldon S. Miller and Robert B. Nussenblatt},
  journal={Journal of immunology},
  volume={181 7},
Noninfectious uveitis is a predominantly T cell-mediated autoimmune, intraocular inflammatory disease. To characterize the gene expression profile from patients with noninfectious uveitis, PBMCs were isolated from 50 patients with clinically characterized noninfectious uveitis syndrome. A pathway-specific cDNA microarray was used for gene expression profiling and real-time PCR array for further confirmation. Sixty-seven inflammation- and autoimmune-associated genes were found differentially… CONTINUE READING
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