Gene expression profiling and pathway analysis of human bronchial epithelial cells exposed to airborne particulate matter collected from Saudi Arabia.

@article{Sun2012GeneEP,
  title={Gene expression profiling and pathway analysis of human bronchial epithelial cells exposed to airborne particulate matter collected from Saudi Arabia.},
  author={Hong Sun and Magdy Y Shamy and Thomas Kluz and Alexandra B Mu{\~n}oz and Mianhua Zhong and Freda Laulicht and Mansour A. Alghamdi and Mamdouh I. Khoder and Lung-chi Chen and Max Costa},
  journal={Toxicology and applied pharmacology},
  year={2012},
  volume={265 2},
  pages={147-57}
}
Epidemiological studies have established a positive correlation between human mortality and increased concentration of airborne particulate matters (PM). However, the mechanisms underlying PM related human diseases, as well as the molecules and pathways mediating the cellular response to PM, are not fully understood. This study aims to investigate the global gene expression changes in human cells exposed to PM(10) and to identify genes and pathways that may contribute to PM related adverse… CONTINUE READING

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