Gene expression profiling: classification of mice with left ventricle systolic dysfunction using microarray analysis.

@article{Wong2010GeneEP,
  title={Gene expression profiling: classification of mice with left ventricle systolic dysfunction using microarray analysis.},
  author={Jim Wong and Christine N Chang and Rani Agrawal and George B Walton and Craig Chen and Ashwin Murthy and Andrew J. Patterson},
  journal={Critical care medicine},
  year={2010},
  volume={38 1},
  pages={25-31}
}
OBJECTIVE We tested the hypothesis that a set of differentially expressed genes could be used to classify mice according to cardiovascular phenotype after prolonged catecholamine stress. DESIGN Prospective, randomized study. SETTING University-based research laboratory. SUBJECTS One hundred seventy-three male mice were studied: wild-type (WT) C57, WT FVB, WT B6129SF2/J, and beta2 adrenergic receptor knockout. INTERVENTIONS Mice of each genotype were randomly assigned to 14-day infusions… CONTINUE READING

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