Gene expression profiles predict survival and progression of pleural mesothelioma.

  title={Gene expression profiles predict survival and progression of pleural mesothelioma.},
  author={Harvey I. Pass and Zhandong Liu and Anil Wali and Raphael Bueno and Susan J. Land and Daniel Lott and Fauzia Siddiq and Fulvio Lonardo and Michele Carbone and Sorin Draghici},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={10 3},
PURPOSE Clinical outcomes for malignant pleural mesothelioma (MPM) patients having surgery are imprecisely predicted by histopathology and intraoperative staging. We hypothesized that gene expression profiles could predict time to progression and survival in surgically cytoreduced pleural mesothelioma of all stages. EXPERIMENTAL DESIGN Gene expression analyses from 21 MPM patients having cytoreductions and identical postoperative adjuvant therapy were performed using the U95 Affymetrix gene… CONTINUE READING
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Prediction of outcome in mesothelioma using gene expression ratios

  • J GordonG., R. V. Jensen, +6 authors R. Bueno
  • J. Natl. Cancer Inst. (Bethesda),
  • 2003
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