Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses

  title={Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses},
  author={Kristine Kleivi and Guro E Lind and Chieu B. Diep and Gunn Iren Meling and Lin Thorstensen Brandal and Jahn Martin Nesland and Ola Myklebost and Torleiv Ole Rognum and K E Giercksky and Rolf I. Skotheim and Ragnhild A. Lothe},
  journal={Molecular Cancer},
  pages={2 - 2}
Despite the fact that metastases are the leading cause of colorectal cancer deaths, little is known about the underlying molecular changes in these advanced disease stages. Few have studied the overall gene expression levels in metastases from colorectal carcinomas, and so far, none has investigated the peritoneal carcinomatoses by use of DNA microarrays. Therefore, the aim of the present study is to investigate and compare the gene expression patterns of primary carcinomas (n = 18), liver… CONTINUE READING


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