Gene expression profiles of genistein-treated PC3 prostate cancer cells.

@article{Li2002GeneEP,
  title={Gene expression profiles of genistein-treated PC3 prostate cancer cells.},
  author={Yiwei Li and Fazlul H. Sarkar},
  journal={The Journal of nutrition},
  year={2002},
  volume={132 12},
  pages={3623-31}
}
Our previous studies have shown that genistein inhibits the growth of PC3 prostate cancer cells and induces apoptosis by inhibiting nuclear factor kappaB (NF-kappaB) and Akt signaling pathways. To better understand the precise molecular mechanism(s) by which genistein exerts its effects on PC3 cells, we utilized cDNA microarray to interrogate 12,558 known genes to determine the gene expression profiles altered by genistein treatment. We found a total of 832 genes that showed a greater than… CONTINUE READING

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