Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis.

@article{Konishi2009GeneEP,
  title={Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis.},
  author={Kazuhisa Konishi and Kevin F. Gibson and Kathleen Oare Lindell and Thomas J. Richards and Yingze Zhang and Rajiv Dhir and Michelle Bisceglia and S{\'e}bastien Gilbert and Samuel A. Yousem and Jin Woo Song and Dong Soon Kim and Naftali Kaminski},
  journal={American journal of respiratory and critical care medicine},
  year={2009},
  volume={180 2},
  pages={167-75}
}
RATIONALE The molecular mechanisms underlying acute exacerbations of idiopathic pulmonary fibrosis (IPF) are poorly understood. We studied the global gene expression signature of acute exacerbations of IPF. OBJECTIVES To understand the gene expression patterns of acute exacerbations of IPF. METHODS RNA was extracted from 23 stable IPF lungs, 8 IPF lungs with acute exacerbation (IPF-AEx), and 15 control lungs and used for hybridization on Agilent gene expression microarrays. Functional… CONTINUE READING

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