Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.

@article{QuekenbornTrinquet2005GeneEP,
  title={Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.},
  author={V Quekenborn-Trinquet and Paul Fogel and O Aldana-Jammayrac and Philippe Ancian and Michel D{\'e}marchez and Patricia Rossio and Helen Louise Richards and Brian Kirby and Chi Nguyen and Johannes J. Voegel and Christopher Griffiths},
  journal={The British journal of dermatology},
  year={2005},
  volume={152 3},
  pages={
          489-504
        }
}
BACKGROUND Psoriasis is characterized by symmetry of plaques and modulation of multiple genes within those plaques. OBJECTIVES We compared gene expression profiles of plaques of psoriasis at different anatomical sites for both symmetrical and asymmetrical disease to ascertain whether the same genes were expressed. METHODS Gene expression profiles were analysed in biopsies from lesional and uninvolved skin from two groups of patients with either predominantly symmetrical or truncal plaques… CONTINUE READING

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