Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers.

@article{Jazaeri2005GeneEP,
  title={Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers.},
  author={Amir Anthony Jazaeri and Christopher S. Awtrey and G. V. R. Chandramouli and Yao Eric Chuang and Javed Khan and Christos Sotiriou and Olga Aprelikova and Cindy J. Yee and Kristin Zorn and Michael J. Birrer and Jeffrey C. Barrett and Jeff Boyd},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2005},
  volume={11 17},
  pages={
          6300-10
        }
}
PURPOSE The goal of this study was to determine whether distinct gene expression profiles are associated with intrinsic and/or acquired chemoresistance in epithelial ovarian carcinoma. EXPERIMENTAL DESIGN Gene expression profiles were generated from 21 primary chemosensitive tumors and 24 primary chemo-resistant tumors using cDNA-based microarrays. Gene expression profiles of both groups of primary tumors were then compared with those of 15 ovarian carcinomas obtained following platinum-based… CONTINUE READING

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