Gene expression profile of zebrafish exposed to hypoxia during development.

@article{Ton2003GeneEP,
  title={Gene expression profile of zebrafish exposed to hypoxia during development.},
  author={C. Ton and D. Stamatiou and C. Liew},
  journal={Physiological genomics},
  year={2003},
  volume={13 2},
  pages={
          97-106
        }
}
  • C. Ton, D. Stamatiou, C. Liew
  • Published 2003
  • Medicine, Biology
  • Physiological genomics
  • Understanding how vertebrates respond to hypoxia can have important clinical implications. Fish have evolved the ability to survive long exposure to low oxygen levels. However, little is known about the specific changes in gene expression that result from hypoxia. In this study we used a zebrafish cDNA microarray to examine the expression of >4,500 genes in zebrafish embryos exposed to 24 h of hypoxia during development. We tested the hypotheses that hypoxia changes gene expression profile of… CONTINUE READING

    Figures and Topics from this paper.

    Transcriptome analysis of the response to chronic constant hypoxia in zebrafish hearts
    80
    Genome-wide mapping of Hif-1α binding sites in zebrafish
    24
    Oxygen-dependent gene expression in fishes.
    246

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 61 REFERENCES
    Hypoxia-induced gene expression profiling in the euryoxic fish Gillichthys mirabilis.
    513
    Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha.
    2197
    Oxygen deprivation causes suspended animation in the zebrafish embryo
    191
    Application of cDNA microarrays in determining molecular phenotype in cardiac growth, development, and response to injury.
    126
    Activation of the heat shock transcription factor by hypoxia in mammalian cells.
    124
    Patterns of Gene Expression During Drosophila Mesoderm Development
    276
    Mechanism, origin, and evolution of anoxia tolerance in animals.
    425
    Molecular basis of hypoxia‐induced erythropoietin expression
    117