Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients.

Abstract

The tumor microenvironment plays an important role in regulating cell growth and metastasis. Recently, we developed an ex vivo lung cancer model (four dimensional, 4D) that forms perfusable tumor nodules on a lung matrix that mimics human lung cancer histopathology and protease secretion pattern. We compared the gene expression profile (Human OneArray v5… (More)
DOI: 10.1002/ijc.28428

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